Idiopathic Inflammatory Myopathies (IIM) Clinical Research Study

The SPIREA Study is evaluating an investigational medication for adults with active idiopathic inflammatory myopathies (IIM).

You may be able to participate if you:

Are at least 18 years of age
Have active IIM confirmed by a physician (such as a rheumatologist, neurologist, or dermatologist)
Are taking standard-of-care medication to treat your active IIM
Meet at least 1 of the following criteria at screening:

Have an active rash associated with IIM
Have a muscle biopsy, muscle MRI, or electromyography report from the past 12 weeks that confirms active IIM
Have any muscle enzyme elevation (this will be tested during the screening period)

If you are interested in participating, the study doctor or staff will review additional study criteria with you.

Qualified participants will receive
all study-required care at no cost.

See If You May Qualify

About Idiopathic Inflammatory Myopathies (IIM)

Idiopathic inflammatory myopathies (also
referred to as myositis) are a group of rare
diseases that share a common trait of muscle
weakness. These diseases include
dermatomyositis (DM), immune-mediated
necrotizing myopathy (IMNM), and anti-
synthetase syndrome (ASyS), among others. 1
Although it’s a rare disease that affects a small
patient population, IIM can affect people of any
age, race, or gender.

IIM is thought to be caused by an overactive
immune system that attacks the body’s own
muscles, skin, and other organs. Idiopathic
means the cause is unknown. 1
Symptoms of IIM result in difficulty
performing typical daily-life activities such
as walking, driving, climbing stairs, rising from
a seated position, turning over in bed, and
raising arms overhead.1, 2

[1] https://understandingmyositis.org/myositis/myositis/
[2] https://www.myositis.org/about-myositis/types-of-myositis/

Diagnosing IIM is challenging, because patients are often misdiagnosed or treated for other diseases for years before a proper diagnosis is made. Dealing with IIM is also challenging, because people with IIM often need to rely heavily on caregivers to complete daily-life activities. There is still a need to find effective treatments for this community, and this is where the SPIREA Study comes in.

See If You May Qualify